Tag: rotavirus

The Contamination of the rota-virus vaccine

expert from VaccineImpact article posted 2017

Looking at the excipient list of vaccines, we can quickly see that every vaccine may be contaminated with at least one animal retrovirus family, all of which have been associated with cancers, chronic liver disease, AIDS, ALS, ME/CFS and autism.

As just one example among hundreds of retrovirus contamination of vaccines, take a look at the history of the rotavirus vaccine. In 2010, the Food and Drug Administration (FDA) convened a panel of experts to review findings that rotavirus vaccines given to infants in the U.S., Rotateq, produced by Merck Pharmaceuticals and Rotarix produced by Glaxo Smith Kline, are contaminated with pig viruses.

Rotarix, an orally administered rotavirus vaccine, contained nucleic acids from porcine circovirus-1 (PCV1) virus and RotaTeq has been shown to contain nucleic acids from both PCV1 and PCV2, a pathogen in pigs that is associated with wasting and immunodeficiency.

While acknowledging that the entire short and long-term risks from the porcine circoviruses PCV1 and PCV2 are as yet unknown, the advisory panel decided that:

“the benefits of the vaccine trumps its risks.”

While the technology to detect genetic contaminates in vaccines was not available until relatively recently, the dangers of generating new viruses and bacteria that can cause diseases were foreseen by the pioneers of genetic engineering. Horizontal gene transfer (HGT) refers to the direct uptake and incorporation of genetic material from unrelated species, in this instance from adventitious viral contaminants in live viral vaccines, into a human host or a host-related bacterium such as those colonizing the gut.

Unlike chemical pollutants which break down and become diluted out, retroviral nucleic acids are infectious, they can invade cells and genomes, multiply, mutate and recombine indefinitely. Potential hazards of HGT of free nucleic acids include the generation of new viruses and bacteria that can cause disease, spreading drug and antibiotic resistance genes among viral and bacterial pathogens making infections untreatable, random insertion into genomes of cells resulting in harmful effects including cancer and reactivation of dormant viruses, present in all cells and genomes, which may cause disease.

Research demonstrates that the pathogenic potential of PCV Type 2 to cause an AIDS-like disease in pigs is unleashed when there is simultaneous immune system activation (e.g. concurrent vaccination) in these animals. Thus, the concurrent inoculation of rotavirus vaccine contaminated with PCV Type 2 DNA sequences along with DTaP, Hib, PCV, IPV and Hep B, as currently recommended by ACIP, provides a high-risk scenario for disease in humans.

PCV Type 2 is a lymphotropic virus that infects primary lymphoid tissues. Its detection in lymphoid tissue of exposed (vaccinated) children should be the focus of urgent investigations, yet relatively few people are aware of the risks.

Such tissue is available in the form of intestinal biopsies from children with a variety of conditions including autism. Lymphatic tissue is also available from rhesus macaques exposed to the current vaccine schedule as part of ongoing safety studies. These tissues should be screened using the same metagenomic and pan-microbial array technology used by Victoria et al to identify adventitious sequences in vaccines.

Every cell line or animal tissue used to manufacture any biological including vaccines must first be cleared of all endogenous viruses in order to prevent the zoonotic transmission of retroviruses to humans and make them safe. Receiving one or two injections of an adventitious retrovirus likely does little damage to a healthy immune system.

However, the aggressive vaccine schedule currently in place means that the number of retroviruses injected into infants, children, and teenagers—including at vulnerable/immune compromised times in their lives—is unknown.

More about retrovirus in vaccines

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